Overview

Karen Best has a big life. She's a big girl with a big personality and a big love of Chardonnay, which occasionally, causes her to make some big mistakes with men. But the biggest thing about Karen is her big heart, a heart she uses to excel at her job as a counselor at a group home for young adults with Down syndrome located in an old brownstone in New York City.

Cast

Bridget Everett

Karen Pittman

Loni Anderson

Luke Zimmerman

Joshua Eber